I know that with my Trane t-stat the lowest it can be set is 55?. Maybe the Vera UI lets you set it lower but the stat will still fire up at 55?. If you want it to go lower I would install some other temp sensors, have Vera turn the heat off entirely and only turn it on when it goes below 35?.
Although, maybe your thermostat lets it go lower than mine does.
Large Humidity and Temperatures variations/cycles, even done over a long period, can put a lot of stress on structural components in your house, if not designed for these.
If your thermostat supports that lowest of a setting, you should be able to modify the app to allow for such a low set point. In the app under Settings → Device Settings, there is a section for thermostats where you can set the min / max for heat and cool.